About the speaker

 

Prof Gunn-Moore studied Biological Sciences at the University of Edinburgh, and then a PhD in Biochemistry at the University of Cambridge. After postdoctoral research at the University of Bristol, Frank returned to Edinburgh, and worked on identifying the protein complex that attaches myelin to neurons. In 2000, he established his own group in St Andrews, studying the development and survival of mammalian neurons.

The prognosis for most neurodegenerative diseases is poor. The causes of the major diseases (eg: Alzheimer's, Parkinson's and Multiple Sclerosis) are complex, including genetic and environmental factors. All conspire to interfere with signalling pathways in neurons and glia which sustain growth and viability. The Gunn-Moore’s group has made major discoveries in understanding the early stages of Alzheimer’s disease, pioneering new models and identifying potential therapeutic targets for the early stages of this disease. Using both molecular and novel biophysical techniques the group has also discovered novel signaling pathways that are involved in the growth and development of mammalian neurons. In addition, to overcome inherent problems with working with cells of the nervous system, the group has developed novel optical technology that allows the manipulation and imaging of these cells.